Rady Children's Hospital San Diego Senior Bioinformaticist-50063 in San Diego, California

Senior Bioinformaticist-50063

Job ID 97 Date posted 04/16/2018 Schedule Full-Time Shift Regular

JOB SUMMARY: Computational-biologists/bioinformaticists in a large-scale 'production' setting to deploy, maintain and evolve the bioinformatics framework for a high-throughput, ultra-rapid turnaround time wholegenome sequencing based clinical setting. Part of a team that'll build the infrastructure ground up using the latest and greatest of the technologies in infrastructure, data storage and analytics, with a strong focus on automation and integration. The environment is highly cross-functional, with a rich medical research heritage and multitude of collaborations with the biotech industry, academic institutions and federal programs.


  • Bachelor's Degree

  • Experience analyzing next-gen sequencing data (Illumina whole genomes or exomes): BCL to annotated variants

  • Experience developing and maintaining pipelines for 24x7 automated bioinformatics analyses

  • Experience working with and understanding of open source NGS tools like bwa, samtools, vcftools, picard, GATK, Freebayes, ANNOVAR, VEP, etc.

  • Experience with unix/linux operating system and software development using any of Ruby, Python, Perl, Bash

  • Experience working with HPC scheduling systems such as Moab, TORQUE, LSF, OpenGrid Engine, etc.


  • Experience in CNV and SV calling Previous experience working in a CAP/CLIA environment Previous experience with cloud-based development or analysis and performing benchmarking of bioinformatics tools

  • Experience with Docker or other container technologies

  • Experience integrating bioinformatics pipeline with other information systems

  • Experience automating next-gen sequencing pipeline

  • Experience with project management

  • Experience offering technical support to upstream laboratory or downstream interpretation personnel